Has anyone taken tramadol hydrochloride acetaminophen for pain?

Damion

I am wondering if it makes you loopy? I have a script for pain, but worried that I will not function well with a 7 year old at home. Any info? I get nervous about painkillers. Thanks!!



Brandee

I was recently prescribed Tramadol 100mg tablets for my tendinits, after a month of using these i felt that i didn't need them anymore.... later did i realise that my body had become dependant on them. I suffered withdrawals such as insomnia, flu like symptoms, headaches, restless legs, depression. I am just passing on my experience of Tramadol, please type tramadol into the 'search for questions' section on yahoo answers for other peoples stories about using Tramadol.Hope you get better soon. x



Dorian

I have taken it all, and it has been just like taking an aspirin, I have not had any problems what so ever.....unfortunately, none of it helped my pain either.........



Hortonville
Jersey City
Mackenzie
West New York
River Vale
Parma Heights

How does the painkiller tramadol work?

Cecila

I also have to write a report on the pharmacology of Tramadol, could someone help me out? Preferably the guy who answered my codeine question.



Helen

Tramadol Hydrochloride (Zydol, Tramacip, Ultram, (Ultracet, Tramacet - when combined with APAP)EffectsTramadol causes instant inhibition of serotonin and norepenephrine reuptake. This leads to increased feeling of wellbeing and happiness.Tramadol itself acts weakly on the μ-opioid (μ is the greek letter Mu) receptors (the ones responsible for euphoria and analgesia).Now, once the Tramadol has been metabolised in the liver, it's M1 metabolite (odesmethyltramadol) then binds to the aforementioned opioid receptors causing a much more powerful euphoria (200x more potent than that of morphine), however, the amount of odesmethyltramadol is quite small, so the potency is relative.The metabolisation must be considered, because not everyone metabolises Tramadol in the same manner, some barely metabolise any into odesmeth... hence many complain that Tramadol is ineffectual. This is the reason why usually.Also, the high from Tramadol lasts longer than that of most other opioids, sometimes up to 16 hours.FormsCapsules (regular and extended release) (Doses usually ranging from 50mg IR (Instant release), 100mg SR (sustained release) to 200mg SR)Tablets (regular, extended release, chewable, low-residue and/or uncoated tablets that can be taken by the sublingual and buccal routes)Suppositories (bypasses hepatic demethylation)Tablets and capsules containing (acetaminophen/APAP), aspirin and other agents. (for analgesic synergy)Effervescent tablets and powdersAmpules of sterile solution for SC, IM, and IV injection (bypasses hepatic demethylation)Preservative-free solutions for injection by the various spinal routes (epidural etc) (bypasses hepatic demethylation)PowdersLiquids with and without alcohol for oral and/or sub-lingual use, available in regular phials and bottles, dropper bottles, bottles with a pump similar to those used with liquid soap and phials with droppers built into the cap.Pharmacokinetic InformationBioavailability = 68 - 72% (this increases with repeated dosing due to increasing amounts of o-desmethyltramadol)Half life = ~5-7 hoursMetabolism = Hepatic demethylation (to odesmethyltramadol) & glucuronidationSide EffectsDrowsinessFatigueConstipationDizzinessNauseaVomitingDry MouthHeadacheIndigestionSeizure (Usually only with overdose)Serious contraindications - Important!SSRI medications can cause too much serotonin to build up in the brain and cause the deadly Serotonin Syndrome! AKA Serotonin Storm!DXM (Dextromethorphan Hydrobromide), because it has Serotonin inhibiting properties and can cause the same syndrome as above.Atypical antipsychotics are also at great risk of causing dangerous interactions when combined with tramadol.Other notable informationAny other route except oral bypasses the hepatic demethylation, weakening the opioid effects of the drug.Although not often warned or mentioned by prescribing doctors, Tramadol DOES have an addiction profile and should be considered an addictive substance if abused.I'm Jacob, who advised you on your codeine question. I've put all the info you'd need on here. Good luck! :)



Mitsuko

Tramadol is a synthetic stripped-down piperidine-analog of the phenantherane alkaloid codeine and, as such, is an opioid and also a pro-drug (codeine is metabolized to morphine, tramadol is converted to M-1 aka O-desmethyltramadol). Opioids are chemical compounds which act upon one or more of the human opiate receptors (the euphoria, addictive nature and respiratory depression are mainly caused by the Mu(μ) 1 and 2 receptor. The opioid agonistic effect of Tramadol and its major metabolite(s) are almost exclusively mediated by the substance's action at the μ-opioid receptor. This characteristic distinguishes tramadol from many other substances (including morphine) of the opioid drug class, which generally do not possess tramadol's degree of subtype selectivity.



Clay

i take tremadol its pretty cool my doc says it tricks the mind into thinkin your on narcotics. makes me feel high. no body pain.



Balta
Kettleman City
Rubidoux
Friona
Margaret
Lakeview

What is tramadol hcl acetaminophen used for?

Jarred

Tramadol hydrochloride and acetaminophen tablets combine two analgesics, tramadol 37.5 mg and acetaminophen 325 mg.Tramadol is a centrally acting synthetic opioid analgesic. Although its mode of action is not completely understood, from animal tests, at least two complementary mechanisms appear applicable: binding of parent and M1 metabolite to µ-opioid receptors and weak inhibition of reuptake of norepinephrine and serotonin. Thus, tramadol has mu-opioid agonist activity.While, acetaminophen is a non-opiate, non-salicylate analgesic.Nonetheless, tramadol hydrochloride and acetaminophen tablets, a tramadol-containing product, can be abused and may be subject to criminal diversion.As for the prescribed usage, it is mostly given to relieve moderate, acute pain such as pain following dental or surgical procedures. Tramadol and acetaminophen each relieve pain, but they do so by different mechanisms. However, there is a high risk of seizure associated with this medication and patients must be well informed of it's any/all side-effects and interactions. Also, prescribing this medication, over 5 days of dosages for acute pain is unreasonable.Good Health To You!



Mammie

A centrally acting analgesic that treats mild to severe pain. The acetmainophen boosts the tramadol's effects. The effects also begin more quickly than generic tramadol and last longer because of the acetaminophen



Garland

It is a combination product used as a mild analgesic. Tramadol is an opioid of sorts, it is very weak and fairly unique. Tramadol is also chemically an antidepressant. It is probably the least addictive opioid and addiction is extremely rare and it is not a controlled substance like morphine, codeine, oxycodone, hydrocodone, and others are. Yes acetaminophen does synergize with Tramadol to some extent but Ultracet, the brand name for tramadol/acetaminophen contains a fairly small amount of tramadol, only 37.5 mg. Regular Tramadol (Ultram is US brand name) without acetaminophen comes in 50 mg tabs/capsules. No more than two Ultracet or Ultram tablets may be taken at one time.



Breana

It's primary indication is for pain management. There are a number of off label uses like:diabetic neuropathy, postherpetic neuralgia, fibromyalgia, restless legs syndrome, opiate withdrawal management / Anti-Depressant withdrawal aid (proven to be effective, especially with withdrawal from its distant relative Venlafaxine (Effexor)),migraine headache, obsessive-compulsive disorder and premature ejaculation.



Jammie

Tramadol (INN) (pronounced /ˈtræmədɒl/) (Tramal, Ultram, Ultram ER, Mabron, Ralivia, Ryzolt, Tradonal, Tramacet, Tridural, Medtrap injs 1ml/2ml and tabs, Ultracet, Zamadol, Zydol, Zytram) is a centrally acting analgesic, used for treating moderate to severe pain.Tramadol was developed by the German pharmaceutical company Grünenthal GmbH in the late 1970s.[1][2]Tramadol possesses agonist actions at the μ-opioid receptor and affects reuptake at the noradrenergic and serotonergic systems.[3][4][5] Tramadol is a compound with mild and delayed μ-agonist activity.Tramadol is a synthetic stripped-down piperidine-analog of the phenantherane alkaloid Codeine and, as such, is an Opioid and also a pro-drug(Codeine gets metabolized to Morphine, Tramadol gets converted to M-1 aka O-desmethyltramadol). Opioids are chemical compounds which act upon one or more of the human opiate receptors(the euphoria, addictive nature and respiratory depression are mainly caused by the Mu(μ) 1 and 2 receptor. The opioid agonistic effect of Tramadol and its major metabolite(s) are almost exclusively mediated by the substance's action at the μ-receptor. This characteristic distinguishes Tramadol from many other substances (including Morphine) of the opioid drug class, which generally do not possess Tramadol's degree of subtype selectivity.en.wikipedia.org/wiki/Ultracet



Willoughby
Lilesville
Belle Prairie City
Leon
Grenora
Shoreview

What is the fatal dose of tramadol hydrochloride?

Danny

My foolish, foolish friend told me over the phone that he took a lot of these from his nans medicine cupboard and took loads at some park (he wouldn't say which one!) I'm really worried about him, what are the chances he might die? How much would he have to have taken?



Calandra

Tramadol is used to relieve moderate to moderately severe pain. Tramadol extended-release tablets are only used by people who are expected to need medication to relieve pain around-the-clock for a long time. Tramadol is in a class of medications called opiate agonists. It works by changing the way the body senses pain.Symptoms of overdose may include: * decreased size of the pupil (the black circle in the center of the eye) * difficulty breathing * extreme drowsiness * unconsciousness * coma * seizure * heart attackNo more information is available.



Chadwick

according to my pharmacist, 300mg. And guys don't hesitate to answer this, because it's medication for restless leg syndrome, so it's very likely it's his friend. But yes, 300 mg based off an average weight of 150, 5ft10. I'm assuming 400 would kill you no matter what, and 100 gets you high.



Danyelle

if he hasn't long taken them you need to make sure he gets to the hospital to get sorted and try to find what he's taken, ask his nan what was in the cupboard as this will help in the hospital treatment, if it was a while ago he took them he still needs to go to the hospital as these drugs will affect his liver and kidney function which can lead to permanent damage of these vital organs, believe me this is no joke



Joetta

Whatisgood..., you need to change your pharmacist. Tramadol is not for restless legs, it is for moderate to severe pain. The starting dose is 25 mg/day, after which you can work up to a maximum of 400 mg/day. The separate question is what is a lethal dose? There is no simple answer to this. In general, pharmacologists speak of an LD50, which is the dose sufficient to kill 50% of a study population. As we don't do lethal experiments on humans, we don't have that answer. The further complication is that tramadol is a drug to which one becomes accustomed, so whether it kills or not depends on the previous degree of exposure.I am sorry that none of this is going to help your friend. Let us hope he is found in time.



Basil

Even if you know the fatal dose, you don't actually know how many exactly your friend has taken -but that's not really the issue here. The most important point is your friend is asking for help by contacting you and you have done the right thing by alerting anyone and everyone who might be able to assist finding him and getting him professional help.You must try to remember though that he is ultimately responsible for his own actions.do let us know



Annamaria

read the link below. u really ought to get him found and to hospital. why would he take these without knowing what they are ??? do his parents know what he has taken as its a little more serious than just searching the local parks. lets hope he is found intime and he learns from it. ps re restless legs it does seem to be one of its uses as per the link



Mitsuko

That is hard to say, mixing alcohol with it can increase the risks.It does not act like a usual narcotic, actually it can stimulate the narcotic receptor very weakly, and the true way it causes pain relief is rather fuzzly understood.Besides supression of breathing and coma, it can also promote convulsions much more than regular narcotics. In fact, if the regular narcotic antidote naloxone is given it helps with breathing but increases the risk of convulsions.Any dose above 300 mg might be a problem but the manufacture does not say much more. Below is an FDA label information pdf file on one brand of the drug.www.accessdata.fda.gov/drugsatfda



Coldstream
Islip Terrace
New Providence
Steele
Corazуn
Jerseytown

What is tramadol hydrochloride 50mg? what is it how does it make you feel and what is is use for?

Deane

painkiller, 50mg is the lowest dose. It will probably make you feel 'numb' to stimuli and a little loopy



Reid

Tramadol is used to relieve moderate to moderately severe pain. Tramadol extended-release tablets are only used by people who are expected to need medication to relieve pain around-the-clock for a long time. Tramadol is in a class of medications called opiate agonists. It works by changing the way the body senses pain.Tramadol can be habit-forming. Do not take a larger dose, take it more often, or take it for a longer period of time than prescribed by your doctor. Call your doctor if you find that you want to take extra medication or if you notice any other unusual changes in your behavior or mood. Do not stop taking tramadol without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking tramadol you may experience withdrawal symptoms such as nervousness; panic; sweating; difficulty falling asleep or staying asleep; runny nose, sneezing, or cough; numbness, pain, burning, or tingling in your hands or feet; hair standing on end; chills; nausea; uncontrollable shaking of a part of your body; diarrhea; or rarely, hallucinations (seeing things or hearing voices that do not exist).



Halbur
Esmond
Absecon
Mosby
Kidder
North Middletown

How do i stop the nausea from tramadol medication?

Chasity

I took a tramadol pill a few hours ago but I didn't have time to eat enough. Now I feel sick and pretty much generally crappy. What can I do to fix the tramadol nausea? What foods should I eat right now to feel better? Would a lot of mac and cheese make me feel better or worse?



Hyacinth

Possible you are not able to handle narcotics....I vomit if I try to take them, so why not call your Dr and ask for something else.



Belinda

Take half a tablet twice as often as you would take a whole pill. Take with yogurt, not something heavy like a Mac.



Glendive
Vista
Mission Woods
Rancho Santa Fe
Ropesville
Hemingway

Is tramadol related in any way to pennicllin?

Alethia

in any way.cuase i bought some tramadol.they are legit.i looked them up.are they related to penicllin in any way



Jenice

No.They have Tylenol in them, so be very careful. Don't take them with other tylenol products or with alcohol.I am thinking of ultracet, which has Tramadol and Tylenol in it. Tramadol generally comes as either ultracet or ultram. Make sure you know which one you have.



Eve

Tramadol is a synthetic (man-made) opiate type drug used for long term pain relief for moderate to severe pain. It does not contain Tylenol it contains Tramadol Hydrochloride. It does not kill germs etc and is not related to penicillin at all.



Adelle

Not related at all. Penicillin is a sort of antibiotic and tramadol is a type of pain relief med



Clarine

No. It is a morphine related drug used for pain management. Penicillan is an antibiotic



Searchlight
Rowesville
Van Meter
Susquehanna Depot
Pocasset
Ronkonkoma

Can tramadol hydrochloride increase the effect of opium?

Andrea

My best friend has recently undergone a surgery and has been prescribed tramadol hydrochloride (50 mg) capsules. But he also intakes opium. so can it increase the effecs of opium?



Isis

Since tramadol is non narcotic I'm guessing the docs already knew of your friends opium use and thats why they prescribed such a crappy pain med.



Alberto

ide consult a pharmacist about drug interactions... but it is never safe to mix when one of the things he is taking isnt prescribed by a doctor



Hubert

Yes



Daggett
Loyola
Fernandina Beach
Laconia
Bishop Hills
Dodge City

Should she be taking this much tramadol?

Catarina

My mom has got rheumatoid arthritis and the doctor has given her 600mg of Tramadol per day (300 morning and evening) should be on a dose this high?



Delores

My doctor did the same for me and I have not had any side affects and it does help my arthritis.



Devon

******************************TRAMADOL FOUND! FULL Information!Best and trusred sites!JUST FOLLOW THE LINK BELOW:>>> aimedsearch.com/search.php?q=tramadol&type=meds&said=anscom <<<CLICK THIS LINK!!! Good Luck!****************************



Alverta

I'd double check with the pharmacist and doctor as it is a narcotic and the dosage is high, above what is recommended for maximum dose, 50% above - from the website I got the below dosage information. www.medicinenet.com/tramadol/artiDOSING: The recommended dose of tramadol is 50-100 mg (immediate release tablets) every 4-6 hours as needed for pain. The maximum dose is 400 mg/day. To improve tolerance patients should be started at 25 mg/day, and doses may be increased by 25 mg every 3 days to reach 100 mg/day (25 mg 4 times daily). Thereafter, doses can be increased by 50 mg every 3 days to reach 200 mg day (50 mg 4 times daily). Tramadol may be taken with or without food.



Isabella

It seems a little high - is it in tablet form or does she have an IV? The maximum dosage differs between the 2 types.You would be better to voice your concerns to her doctor though and ask them to explain their reasoning as you understand that 400mg in tablet form is normally the maximum recommended dose.



Carmina

It does seem a lot, I would be inclined to query the dose.Tramadol is addictive and you can also develop a tolerance to it (so you need more for the same effect).As her doctor has prescribed it tread carefully as she might be in so much pain that she needs that amount.We can only speculate, she and her doctor are the only ones to decide what is necessary to keep her pain free. They know the facts, we don't.



Jenae

This is what I found on Tramdol....Honey this is a Narcotic and they gave it to my daughter whom is 15 and she was so very sick from this drug....tell her to be soooooooooo very careful....it is very addicting and she can go into withdrawls if she abruptly stops taking it...but I cannot say either way I am not a doctor....just read up and watch her for the side effects.....Love To You....Ultram is the same as Tramadol...Tramadol is the generic...It says the maximum dosage is 400 mgs per day...read up babe...I Hope This Helps You.....UltramGeneric name: Tramadol hydrochlorideBrand names: UltramWhy is Ultram prescribed? Feedback for UltramPain Fibromyalgia Restless Legs Syndrome Ultram or Tramadol is prescribed to relieve moderate to moderately severe pain.Most important fact about UltramYou should not drive a car, operate machinery, or perform any other potentially hazardous activities until you know how Ultram affects you.How should you take Ultram?It's important to take Ultram exactly as prescribed. Do not increase the dosage or length of time you take Ultram without your doctor's approval.--If you miss a dose...Take it as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.--Storage instructions...Store in a tightly closed container at room temperature.What side effects may occur?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Ultram.More common side effects may include:Agitation, anxiety, bloating and gas, constipation, convulsive movements, diarrhea, dizziness, drowsiness, dry mouth, feeling of elation, hallucinations, headache, indigestion, itching, nausea, nervousness, sweating, tremor, vomiting, weakness Why should Ultram not be prescribed?Avoid Ultram if it has ever given you an allergic reaction. Also avoid Ultram after taking large doses of sleeping pills such as Halcion, Dalmane, and Restoril; narcotic pain relievers such as Demerol, morphine, Darvon, and Percocet; or psychotherapeutic drugs such as antidepressants and tranquilizers. And do not take Ultram after drinking excessive amounts of alcohol.Special warnings about UltramIf you have stomach problems such as an ulcer, make sure your doctor is aware of them. Ultram may hide the symptoms, making them difficult to diagnose and treat.Ultram can cause mental and physical addiction. If you've ever had a problem with narcotic painkillers such as Percocet, Demerol, or morphine, you should avoid Ultram. Withdrawal symptoms may occur if you stop taking Ultram abruptly. Such symptoms include anxiety, sweating, insomnia, pain, nausea, tremor, diarrhea, and respiratory problems. A gradual decrease in dosage will help prevent these symptoms.Do not take more than the recommended dose of Ultram, since larger doses have been known to cause seizures, especially if you have epilepsy or are taking medications that also increase the risk of seizures. Among such medications are almost all antidepressant drugs, plus narcotics and major tranquilizers such as Loxitane and Stelazine.If you have liver or kidney disease, be sure your doctor knows about it. Your dosage may have to be reduced.Before you have any kind of surgery, make sure the doctor knows you are taking Ultram.If you have any kind of breathing problem, use Ultram with caution or take a different kind of painkiller. Ultram can impair respiration, especially if taken with alcohol.If you have experienced a head injury, consult your doctor before taking Ultram. The medication's effects may be stronger and could hide warning signs of serious trouble.Possible food and drug interactions when taking UltramUltram may increase the drowsiness caused by alcohol. Do not drink alcohol while taking Ultram.Avoid Ultram, too, if you are taking the seizure medication Tegretol.If Ultram is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Ultram with the following:Cyclobenzaprine (Flexeril)Drugs known as MAO inhibitors, including the antidepressants Nardil and ParnateSerotonin-boosting antidepressants such as Paxil, Prozac, and ZoloftTricyclic antidepressants such as Elavil, Norpramin, and TofranilMajor tranquilizers such as Thorazine and StelazineNarcotic pain relievers (Demerol, morphine, Darvon, Percocet)Promethazine (Mepergan, Phenergan)Quinidine (Quinidex)Sleeping pills (Halcion, Dalmane, Restoril)Tranquilizers (Valium, Xanax)Special information if you are pregnant or breastfeedingThere have been reports of serious harm to developing babies when Ultram was used during pregnancy. If you are pregnan



Assunta

How should I take tramadol?Take tramadol exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Follow the directions on your prescription label. Do not take more than 300 milligrams of tramadol in one day.Take this medication with a full glass of water.Tramadol can be taken with or without food, but take it the same way each time.Do not crush the tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death. Do not crush, chew, break, or open a controlled-release, delayed-release, or extended-release tablet or capsule. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.If you use the tramadol extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.Tramadol may be habit-forming. Tell your doctor if you feel the medicine is not working as well in relieving your pain. Do not change your dose without talking to your doctor. Do not stop using tramadol suddenly, or you could have unpleasant withdrawal symptoms such as anxiety, sweating, nausea, diarrhea, tremors, chills, hallucinations, trouble sleeping, or breathing problems. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. Store tramadol at room temperature away from moisture and heat. Keep track of how many pills have been used from each new bottle of this medicine. Tramadol is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.



Belinda

hiya,i was taking that amount,but it was not helping the pain.they have now put me on morphine,and im pain free.



South Orange
Kulpmont
Pensacola
Ferrum
Miller City
Cayce

Can you take tramadol and tramacet at the same time?

Tawnya

ive only got 1 50mg of tramadol left and i take 2 every 4 hours but ive got some, Tramacet 37.5 mg/325 mg film-coated tablets (Paracetamol, Tramadol hydrochloride) so cud i take 1 tramadol and 1 tramacet at same time? thanks



Dianna

Yes, you can safely take both simultaneously. Tramadol is a pain reliever and Ultracet is tramadol +tylenol. By combining the two pills, you are getting a near optimal dose of tramadol plus some tylenol, which shouldn't hurt unless your liver is a mess



Hampshire McBain Milton North Sultan Plentywood Valley Brook